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Welcome to Heart Health Care, LLC
29th Nurse Practitioner Symposium
July 15-18, 2004
Keystone, Colorado
Update on Dyslipidemia Rx LE
Industry Sponsored Symposium July 16th
Recognize how to select the appropriate lipid-lowering agent (LLA) or agents for lipid abnormalities; steps for using combination therapy to avoid adverse outcomes; and the use of LLA in the elderly, women and children. Case studies will be used throughout the program. Audience
participation is encouraged; bring your difficult lipid profiles.
Frances Stier, MSN,ANP,ACNP;
Nurse Practitioner,
Northern Arizona Heart Center; Show Low AZ
Sponsored by an unrestricted educational grant from AstraZeneca.
Materials from Fran's presentation:
- Objectives: At the end of the presentation, the speaker hopes that the participants will be able to:
- Apply the ATP III guidelines to specific patient profiles.
- Select the appropriate lipid-lowering agent (LLA) for the lipid abnormality.
- Describe the indications and monitoring for combination therapy.
- Describe the benefits of statin therapy beyond lowering of cholesterol.
- Describe lipid-lowering in special populations.
- Outline:
- Summarize key points of the ATP III guidelines
- Lipoproteins and subfractions.
- Medical conditions that indicate CAD equivalent.
- Calculating 10-year risk for CAD.
- Lipid-lowering agents: categories, indications, dose, and effect on specific lipoproteins and triglycerides.
- Steps to follow in using combination therapy.
- Monitoring for ADRs
- Beyond lipid-lowering: stroke prevention and plaque stabilization.
- When to use LLA in the elderly, women and children
- Bibliography:
- Bussoletti A. Framingham Point Score: A useful tool in assessing CHD risk. The Journal for Nurse Practitioners. 2003; 7(9): 17-24.
- Executive Summary of the Third Report of the National Cholesterol Educational Program (NCEP) Expect Panel on Detection, Evaluating and Treatment of High Blood Cholesterol in Adults (ATP III). JAMA. 2001;285(19):2486-2497.
- Foody JM, Krumlotz HM. Are statins indicated for the primary prevention of CAD in octogenarians? Antagonist viewpoint. The Am.Joun.Geriatric Cardiology. 2003;12(6):357-360.
- Jones PH, Davidson MH, Stein EA, et.al. Comparison of the efficacy and safety of Rosuvastatin versus Atorvastatin, simvastatin, and Pravastatin across doses (Stellar Trial). The American Joun. Of Cardiology. 2003;92:152-160.
- MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin of 20,536 high-risk individuals: a randomized placebo-controlled trial. Lancet. 2002;360(9326):7-22.
- Pasternak RC, Smith SC,jr., Baiirey-Merz CN, Grundy SM, Cleeman JR, Lenfant C. ACC/AHA/NHLBI Clinical advisory on the use and safety of statins. Circulation. 2002;106(8):1024-1028.
- Stone NJ. an Are statins indicated for the primary prevention of CAD in octogenarians? Protagonist viewpoint. The Am.Joun.Geriatric Cardiology. 2003;12(6):351-354.
- Internet Resources:
- www.Nhlbi.nih.gov/guidelines/cholesterol/atpiii.htm
- www.heartcenteronline.com The Cholesterol Center. Palm OS applications. 10-year Risk Calculator
- www.lipidhealth.org
- www.americanheart.org
- Seminar Handout* (183Kb)
- Slide presentation* (2.3Mb - 11 min @ 28.8Kbps)
* To view these materials in PDF format, you will need the FREE Adobe Acrobat Reader, available here: 
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